Going the distance—insights into how cancer cells spread

Most tumors consist of a heterogenous mix of cells. Genetic mutations found only in some of these cells are known to aid with the spread and progression of cancer. However, oncologists often find that when tumors metastasize to distant organs, they retain this heterogenous nature—a phenomenon termed ‘polyclonal metastasis.’ The mechanism by which non-metastatic cells […]

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Researchers find parallels in spread of brain cancer in mammals, zebrafish

Scientists at the Fralin Biomedical Research Institute at VTC have identified a new zebrafish model that could help advance glioblastoma multiforme research. Glioblastoma is an aggressive form of primary brain tumor—fewer than one in 20 patients survive five years after diagnosis. The research team previously discovered that human-derived brain cancer cells in mice use the […]

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